@article { author = {Zangeneh, Farideh and Abedinia, Nasrin and Mehdi Naghizadeh, Mohammad and Salman Yazdi, Reza and Madani, Tahereh}, title = {The Effect of Ramadan Fasting on Hypothalamic Pituitary Ovarian (HPO) Axis in Women with Polycystic Ovary Syndrome}, journal = {Women’s Health Bulletin}, volume = {1}, number = {1}, pages = {1-6}, year = {2014}, publisher = {Shiraz University of Medical Sciences}, issn = {2345-5136}, eissn = {2382-9990}, doi = {10.17795/whb-18962}, abstract = {Background: Ramadan fasting is a religious practice and an exceptional ritual compared to all other religious conventions. The aim of fasting in Ramadan is to establish a proper religious model of self-control and healthy lifestyle. Objectives: The purpose of this study was to compare the biochemical neurohormones between women with polycystic ovary syndrome (PCOS) with and without fasting. Materials and Methods: This study was conducted during July 2011 at the Infertility Center of Royan Institute, and comprised 40 patients diagnosed with PCOS, aged from 20-40 years without any special disease. The study group included 20 women with PCOS and fasting during Ramadan. The control group consisted of 20 non-fasting women with PCOS. The study on the effects of fasting on patients with polycystic ovary syndrome involved demographic data and biochemical stress hormones including cortisol, adrenaline, noradrenaline, beta-endorphin and insulin. Results: In patients with PCOS, mean of cortisol in subjects with and without fasting were 8.2 ± 4.4 and 11.2 ± 4.7, respectively (P = 0.049). Also the respective median of nor-adrenaline in fasting and non-fasting patients were 1273.5 and 1503.5 (P = 0.047). However, no significant differences were found in adrenalin (P = 0.151), beta-endorphin (P = 0.543) and insulin (P = 0.818) between PCOS two groups. Conclusions: This study showed that Ramadan fasting is a well known practice to reduce stress hormones in women with PCOS. So, Ramadan, beside its spiritual benefit is a blessing from God for improving human lifestyle.}, keywords = {Ramadan fasting,Polycystic ovary syndrome,Stress hormones,Beta,endorphine,Insulin,Sex hormones}, url = {https://womenshealthbulletin.sums.ac.ir/article_45174.html}, eprint = {https://womenshealthbulletin.sums.ac.ir/article_45174_395b57b1888b8bf45feabf5d5ec1c7d0.pdf} }