Document Type : Case Report

Authors

Department of Obstetrics and Gynecology,School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Abstract

Introduction:Herlyn-Werner-Wunderlich Syndrome (HWWs) is a rare variant of Mullerian duct anomalies. It is associated with a wide range of gynecological and obstetric complications, such as urinary incontinence, urinary retention, endometriosis, pelvic infection, pelvic pain and infertility.
Case presentation: We conducted the present study to investigate and manage HWWs with pelvic pain. The surgery was performed on the operative room of Imam Reza Hospital in April 2018.
Conclusion: The reported case is related to Herlyn-Werner-Wunderlich Syndrome, a rare congenital Mullerian duct anomaly, which it is not included in the current classification system of the Mullerian abnormalities of the American Fertility Association and is based on the typical pattern of caudal evolution towards cranial.

Keywords

1. Arleo EK, Troiano RN. Complex Mullerian Duct Anomalies Defying Traditional Classifica tion: Lessons Learned. J IVF Reprod Med Genet. 2013;1:3. doi: 10.4172/2375-4508.1000115. ## 2. Grimbizis GF, Gordts S, Di Spiezio Sardo A, Brucker S, Angelis CD, Gergolet M, et al. The ESHRE/ESGE consensus on the classification of female genital tract congenital anomalies. Hum Reprod. 2013;28(8):2032-44. doi: 10.1093/humrep/det098. PubMed PMID: 23771171; PubMed Central PMCID: PMC3712660. ## 3. Mangla R, Kaur T, Pathak N. Septate uterus with cervical duplication and a longitudinal vaginal septum: an unclassified mullerian anomaly. International Journal of Reproduction, Contraception, Obstetrics and Gynecology. 2016;5(2):536-38. doi: 10.18203/2320-1770.ijrcog20160406. ## 4. Khaladkar SM, Kamal V, Kamal A, Kondapavuluri SK. The Herlyn-Werner-Wunderlich Syndrome - A Case Report with Radiological Review. Pol J Radiol. 2016;81:395-400. doi: 10.12659/PJR.897228. PubMed PMID: 28058067; PubMed Central PMCID: PMC5181573. ## 5. Zhu L, Chen N, Tong JL, Wang W, Zhang L, Lang JH. New classification of Herlyn-Werner-Wunderlich Syndrome. Chin Med J. 2015;128(2):222-5. doi: 10.4103/0366-6999.149208. PubMed PMID: 25591566; PubMed Central PMCID: PMC4837842. ## 6. Wai C, Zekam N, Sanz LE. Septate uterus with double cervix and longitudinal vaginal septum. A case report. J Reprod Med. 2001;46(6):613-7. PubMed PMID: 11441691. ## 7. Ribeiro SC, Yamakami LYS, Tormena RA, Pinheiro WDS, Almeida JAMDA, Baracat EC. Septate uterus with cervical duplication and longitudinal vaginal septum. Rev Assoc Med Bras. 2010;56(2):254-6. doi: 10.1590/s0104-42302010000200029. PubMed PMID: 20499005. ## 8. Sonawane PK, Bhavsar UC. Complete septate uterus with cervical duplication and longitudinal vaginal septum: an uncommon mullerian anomaly. Int J Reprod Contracept Obstet Gynecol. 2015;4(6):2065-68. doi: 10.18203/2320-1770.ijrcog20151318. ##