Sedigheh Sakkaki; Farah Naderi; Fariba Hafezi
Abstract
Background: The diagnosis of cervical cancer significantly affects the health-related quality of life (HRQOL) of women. This study aimed to investigate the relationships between chronic fatigue syndrome (CFS) and experiential avoidance (EA) with HRQOL, mediated by depression in women with cervical cancer.Methods: ...
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Background: The diagnosis of cervical cancer significantly affects the health-related quality of life (HRQOL) of women. This study aimed to investigate the relationships between chronic fatigue syndrome (CFS) and experiential avoidance (EA) with HRQOL, mediated by depression in women with cervical cancer.Methods: This descriptive-correlational study selected 261 cervical cancer cases in Mashhad, Iran in 2021, using purposive sampling from October 10, 2021 to December 24, 2021. The research tools include the SF-36 Questionnaire, the Chalder Fatigue Scale, the Brief Experiential Avoidance Questionnaire, and Beck Depression Inventory. Data analysis was done using Pearson correlation coefficient and structural equation modeling in SPSS version 27 and AMOS version 24.Results: The results indicated that all direct paths, with the exception of CFS, significantly correlated with HRQOL (P<0.001). Depression mediated the significant indirect paths of CFS to HRQOL and the significant relationship between EA and HRQOL (P<0.001).Conclusions: The findings of this study revealed that CFS and EA were negatively related to HRQOL in women with cervical cancer. Moreover, depression mediated the relationship of CFS and EA with HRQOL.
Wahida A Ibrahim; Shameran Daniel; Nawfal R Hussein; Mahde Saleh Assafi; Ramadan Othman
Abstract
Background: Human Papillomavirus infection is sexually transmitted and associated with several cancers, such as cancer of the cervix, vagina, vulva, head and neck, anal, and penile carcinoma. Health education plays a pivotal role in building knowledge and positive attitude about health issues.
Objectives: ...
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Background: Human Papillomavirus infection is sexually transmitted and associated with several cancers, such as cancer of the cervix, vagina, vulva, head and neck, anal, and penile carcinoma. Health education plays a pivotal role in building knowledge and positive attitude about health issues.
Objectives: The current study aimed at assessing the knowledge of final and pre-final students of colleges of medicine and nursing.
Methods: This cross-sectional study was performed between September 2017 and December 2017. The project was carried out in the College of Nursing and Azadi Teaching Hospital of Duhok, Iraq. An HPV knowledge questionnaire was used covering three HPV-related subjects, including cervical cancer-HPV association, HPV features, and HPV vaccines. All final and pre-final students of the college of medicine and nursing were recruited.
Results: In cervical cancer-HPV association knowledge dimension, which composed of four questions, there were significant differences in knowledge regarding HPV-cancer association (77.6% for medical students versus 51.6% for nursing students, P < 0.001) and cancer prevention (81.9% versus 38.7%, P < 0.001), when the correct answers were stratified according to college. When the answers were stratified according to the study years, significant differences were found in awareness about the detection of HPV in cervical cancer between pre-final and final year students in college of medicine (68.3% for pre-final versus 87.5% for final P = 0.02) and college of nursing (33.3% versus 72.4%, P < 0.001). Then, the researchers tested awareness of HPV features and there were significant differences in the awareness of students between both colleges (P < 0.01 for all questions). A significant difference was found between males and females when they were asked about the genotypes and cervical cancer (67.3% for males versus 78% for females P = 0.043). Finally, this research tested the awareness of students about HPV vaccine. The participants were asked whether HPV vaccine protects against all STD; 81.9% of medical students and 60.5% of nursing students gave correct answers (P < 0.001).
Conclusions: The knowledge of students varied according to college, study year, and gender. Attention must be paid to HPV and quick revision is mandated to increase the awareness of students.
Mojtaba Oraki Kohshour; Manijeh Afra; Abdolhossein Shakurnia; Nepton Emad Mostofi; Behnaz Andashti
Abstract
Background: Cervical cancer ranked as the most common cancer of women in developing countries. Human Papillomaviruses (HPVs) belongs to the Papillomaviridea family, which is able to infect humans. Some HPV types are the causes of getting cervix cancer and it is clear that persistent infection, with a ...
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Background: Cervical cancer ranked as the most common cancer of women in developing countries. Human Papillomaviruses (HPVs) belongs to the Papillomaviridea family, which is able to infect humans. Some HPV types are the causes of getting cervix cancer and it is clear that persistent infection, with a high - risk HPV genotypes, is known to be a major carcinogenic factor.
Objectives: Determining the HPV genotypes distribution in women with cervical cancer in Khuzestan province, which is located in the southwest of Iran, to help design better preventive and also therapeutic strategies for promoting women health.
Methods: A total of 75 archival cervical carcinoma tissue samples were studied for the presence of HPV DNA and determination of the genotypes by PCR and Sequencing. Genomic DNA was extracted from the FFPE cervical tissues and then subjected for the PCR based amplification with subsequent direct sequencing of the HPV positive PCR products.
Results: The mean age of patients was 56. There were 42 samples with HPV DNA by using GP5+ and GP6+ primers. The result of HPV genotyping have been distinguished as follow: 33 samples as HPV-16, 4 samples as HPV-18, 1 sample for each HPV-54, 56 and 58 genotypes, and 2 samples remained unknown.
Conclusions: Detecting HPV genotypes absolutely shed light on guidelines cervical cancer screening and vaccination policy in our country and in other developing countries. Collectively, our results suggest that HPV-16 is the frequent high - risk HPV type in our geographical area. HPV genotype testing, as a primary screening tool, plays an important role in cervical cancer prevention and therefore, it is a strongly recommended vaccination against HPV, especially for high school girls be included in the national immunization program.
Ali Khani Jeihooni; Seyyd Mansour Kashfi; Mina Bahmandost; Seyyd Hannan Kashfi
Abstract
Background: Cervical cancer is the second most common cancer among women in the world and the most frequent in developing countries. Secondary prevention, achieved through Pap smear testing, is the single most effective tool in reducing deaths due to cervical cancer.
Objectives: The aim of this study ...
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Background: Cervical cancer is the second most common cancer among women in the world and the most frequent in developing countries. Secondary prevention, achieved through Pap smear testing, is the single most effective tool in reducing deaths due to cervical cancer.
Objectives: The aim of this study was to assess factors affecting Pap smears in women based on the Health Belief Model in health centers of Fasa, Iran.
Patients and Methods: This cross-sectional study comprised a total of 200 randomly selected married women who referred to health centers in Fasa, Iran. The participants responded to the standard questionnaire. The data obtained were analyzed using SPSS 18.
Results: In this study, approximately 25% of the subjects had a history of the test. The mean score of all health belief model-related perceived variables including susceptibility, severity, benefits and barriers in patients with a history of the test was higher than those without a history. Analyzing the data using independent t-test showed a significant difference between the mean scores of all HBM structures with performing Pap test in patients with a history of the test. The most important reason for performing the Pap test by subjects was the health professionals’ advice (84%), and the main reason for not performing the test by subjects was their belief that they are not susceptible to cancer.
Conclusions: Women’s health care professionals play effective roles in informing women about factors related to cervical cancer screening. According to the results, it would be beneficial to design strategies for reducing barriers to Pap smear test among women.
Pegah Jahani; Sulmaz Ghahramani; Gholamreza Abdollahifard
Abstract
Background: Due to the increasing rate of cervical cancer screening, and the importance of teachers and faculties in changing the perspective of population on this issue, the present study was carried out to evaluate knowledge base, attitude and performance of teachers and faculty members in relation ...
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Background: Due to the increasing rate of cervical cancer screening, and the importance of teachers and faculties in changing the perspective of population on this issue, the present study was carried out to evaluate knowledge base, attitude and performance of teachers and faculty members in relation to cervical cancer screening test.
Objectives: This study attempted to evaluate the knowledge, attitude and performance of teachers and faculty members on cervical cancer screening test in Shiraz, Iran.
Patients and Methods: The present cross-sectional survey was conducted on a community with high education level. The study was carried out on a sample of 417 randomly selected subjects involving 206 participants from high school teachers and 211 faculty members. Stratified random sampling method was used proportionate to the size, of the main population in each group. P value 0.05 was considered for estimating sample size. Valid and reliable questionnaires were completed via face to face interview. Data were analyzed using SPSS Software version 13.
Results: Mean score of knowledge (4.78 ± 0.71) was higher in faculty members than female teachers (4.21 ± 1.16). There was no statistically significant difference in mean scores of knowledge (P value = 0.748) and attitude (P value = 0.704) between teachers of different age groups. Mean score of knowledge (P value = 0.001) and attitude (P value = 0.009) was significantly different among faculty members with different academic degrees. Although academics had higher Knowledge and attitude, the mean score of performance among teachers (18%) was higher than faculty members (16.6%).
Conclusions: This study showed that in regard to screening of cervical cancer, there is no acceptable knowledge, attitude and performance level among faculty members and teachers in different zones of Shiraz.
